Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in 1 hippocampal area CA 1
نویسندگان
چکیده
Department of Biology, University of Pennsylvania, Philadelphia, PA, 19104, United States; 6 Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen, Groningen, 7 The Netherlands; Institute of Cardiovascular and Medical Science, Wolfson and Davidson Buildings, 8 College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, 9 Scotland, United Kingdom, LSA Molecular, Cellular, and Developmental Biology, Kraus Building, 10 University of Michigan, Ann Arbor, Mi, 48109, United States; Laboratory of Molecular Basis of 11 Behavior, Nencki Institute of Experimental Biology, 02-093 Warsaw, Pasteura 3, Poland. Institute of 12 Pharmaceutical Science, King's College London, Franklin-Wilkins Building, London SE1 9NH, 13 United Kingdom, Current address: Department of Psychiatry Columbia University and the New York 14 State Psychiatric Institute, 1051 Riverside Drive, New York, NY, 10032, United states. 15 16 17 * corresponding authors 18
منابع مشابه
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1
Brief periods of sleep loss have long-lasting consequences such as impaired memory consolidation. Structural changes in synaptic connectivity have been proposed as a substrate of memory storage. Here, we examine the impact of brief periods of sleep deprivation on dendritic structure. In mice, we find that five hours of sleep deprivation decreases dendritic spine numbers selectively in hippocamp...
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